Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) on the safety of mpox vaccines for use in high-risk groups

No images? Click here Friday, 04 October 2024 STATEMENT The safety of mpox vaccines for use in high-risk groups The WHO Global Advisory Committee on Vaccine Safety (GACVS) today published a statement on the safety of mpox vaccines for use in high-risk groups. Highlights: GACVS reviewed three mpox vaccines (MVA-BN, LC16m8, ACAM2000) in December 2022, and following the declaration of a PHEIC in 2024 reaffirmed its position in 2024 on the use of these vaccines, with ongoing guidance for safety and usage in vulnerable populations. On 20 September 2024, WHO GACVS discussed the safety of two 3rd generation vaccines (MVA-BN and LC16m8) based on post-approval data from global agencies and highlighted the need for further studies, particularly for infants, pregnant women and immunocompromised people. The GACVS recommends close safety monitoring of mpox vaccines, especially in high-risk populations, and emphasized training for healthcare workers on proper vaccine administration techniques to minimize adverse events. The Committee stressed the importance of using standardized protocols for vaccine safety surveillance, especially in populations like infants, children, pregnant women, and people living with HIV, with tools like Vigiflow and VigiMobile and other software supporting adverse events reporting and investigation efforts. The full text of the statement can be accessed here: https://www.who.int/news/item/04-10-2024-statement-gacvs-safety-mpox-vaccines-for-use-in-high-risk-groups Related links: https://www.who.int/emergencies/situations/mpox-outbreak Overview of Mpox (monkeypox) vaccines and safety surveillance, World Health Organization, 2023 Smallpox and mpox (orthopoxviruses): WHO position paper, August 2024 Media contacts: mediainquiries@who.int   You are receiving this NO-REPLY email because you are included on a WHO mail list. If you have been forwarded this update you can click here to subscribe. Journalists may send feedback to WHO Media Team       Share    Tweet    Share    Forward  World Health Organization, Avenue Appia 20, 1202 Geneva 27, Switzerland  Preferences  |  Unsubscribe